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Acute esophageal necrosis : ウィキペディア英語版
Acute esophageal necrosis

Acute esophageal necrosis (AEN), also known as Gurvits Syndrome, Black Esophagus, acute necrotizing esophagitis, and esophageal infarction; is a rare esophageal disorder. AEN defines itself with dark pigmentation of the esophagus, found during an upper gastrointestinal endoscopy. Pigmentation is usually black friable mucosa.〔http://web.ebscohost.com/ehost/pdfviewer/pdfviewer?vid=4&hid=5&sid=f15ae0b5-79ab-4288-9025-3856e725b220%40sessionmgr4〕 The disorder is extremely rare, as only 88 patients over a span of 40 years have received this diagnosis.〔 Specific study of the disorder's mortality rate is mentioned at 31.8%,〔 but new research suggests mortality rates vary from 30-50%.〔 The exact triggering mechanism for this disorder is still unknown, but is likely a multifactorial.〔
==Signs and symptoms==
AEN has never been recorded as a one symptom disorder, but instead present by multiple symptoms.〔 The symptoms vary from the severity of the disorder. The most classic sign of AEN is the dark pigmentation of esophageal mucosa in an upper endoscopy, usually viewed as an ulcer or as an infectious disease.〔 Necrosis can be found mostly between the three distals of the esophagus, but stops abruptly at the gastroesophageal junction.〔 The basic and most common symptoms reported are blood in stool and blood in vomiting. Upper gastrointestinal bleeding then is reported, and is very commonly represented in elderly patients. Black or bloody stools and hematemesis account for over three quarters of the case presentations. Abdominal pain, nausea, vomiting, and unstable vital signs are common. A cardiovascular event (such as a heart attack) was reported in ten percent of the total known cases.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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